Showing posts with label Clinical Overview of abortion. Show all posts

Anthrax


Anthrax

Definition of antrax
Anthrax is a disease in wild animals, or pets, namely ruminant animals (herbivores), such as cows, buffaloes, goats, sheep, pigs and horses. The disease is transmitted to humans, especially in people who his work is always associated with / adjacent to livestock such as farmers, shepherds, veterinarians, laboratory workers, factory workers, goods leather goods and bones.





Cause of antrax

Germs of anthrax (Bacillus anthracis)
Modes of Transmission
The disease is usually transmitted to humans by the entry of spores or anthrax bacilli into the body through various ways, namely through skin abrasions or injury that causes skin anthrax, through the mouth as food ingredient contaminated food, resulting in intestinal anthrax (gastrointestinal), inhalation respiratory tract causing pulmonary anthrax. Antrak inflammation of the brain (Meningitis) usually is a form of continuation of skin anthrax, intestinal or
pulmonary. Pulmonary anthrax is very rare and meningitis were reported in Indonesia.
Transmission occurs by direct contact with the animal patient, eg contact with blood coming out of the holes kumlah animals died due to anthrax or ingredients of animal origin contaminated by spores anthrax, such as meat, offal, hides, flour, wool, and so forth. Besides the that, other potential sources of transmission is ligkungan, among other lands, crops (vegetables) and water contaminated by anthrax spores.


Clinical Overview
A. Anthrax Clinical Skin
- The incubation period of 7 days (average 1-7 days)
- Itching spot lesions
- Papel
- Vesicles
- Ulcer (ulcers) in the middle there is a form of scab of necrotic tissue black (pathognomonic sign of anthrax) and is usually obtained erythema and edema around the ulcer. At the touch, edema is not soft and does not dent (non-pitting) when pressed. Here is obtained pus unless secondary infection followed.
- There can be enlarged regional lymph nodes
- A fever that is, headache, malaise rare
- Predilection for skin anthrax is usually in open places, such as face, neck, arms, hands, and feet
- Untreated skin anthrax will grow worse with spreading to the lymph nodes and continue into the bloodstream, thereby lead to septicemia and possible death of 5-20%
- Bacteriological examination of exudates in skin lesions obtained bacilli in the preparation of clear and positive culture.

2. Clinical Intestinal Anthrax
- The incubation period varies from 2-5 days
- Early symptoms of nausea, no appetite, and temperature rise
- Vomiting
- Severe abdominal pain
- Constipation
- Can also occur with acute gastro-enteritis is sometimes bloody, hematemesis, general weakness, fever and no history of exposure with animals or food products.
- Bacteriological Examination of stool specimens obtained from the bacillus removed and preparation of the positive culture.

Diagnosis
A. Skin anthrax suspect
If a case or "explosion" or a history of anthrax in animals exposure to animals / materials of animal origin and the polluted environment by spores / bacilli of anthrax and found abnormalities in the form of skin ulcers the dead tissue form a black scab in the middle (eskar),
redness around the ulcer, swollen, swollen area on the palpability is not soft and does not dent and is usually not found except pus Primary infection is followed sekunder.

2. People with skin anthrax (definite diagnosis)
If on skin anthrax suspect the diagnosis confirmed by bacteriological examination.

3. Intestinal anthrax suspect
If a case or "explosion" or a history of anthrax in animals exposure to animals or food products and found the heat accompanied by abdominal pain and vomiting.

4. Patients with intestinal anthrax (definite diagnosis)
If on skin anthrax suspect the diagnosis confirmed bybacteriological examination.

Management of anthrax
- Drug of choice (drug of choice) for patients with skin anthrax is penicillin.
Procain penicillin 1.2 million IU im dose of 2 x day for 5-7 days
or benzylpenicillin 250 000 IU dose every 6 hours. Before granting
do penicillin skin test. Patients who are hypersensitive to penicillin
tetracycline can be administered at a dose of 500 mg, 4 times daily for 5-7 days.
Should not be given to children under 6 years. Alternative medicine
is chloramphenicol.
- The intestinal anthrax may be given penicillin G 18-24 million units per day
intravenously, can be added tetracycline 1 g per day.
- Symptomatic medications and supportive if necessary
- Refer to hospital if necessary.

Prevention of Anthrax
- Public asked to report to the local health clinic if there is a suspect Animal anthrax and reported to the animals when there are sick with symptomsanthrax
- It is forbidden to slaughter sick animals anthrax
- It is forbidden to consume meat from animals that anthrax illness
- Not allowed to create items of animal origin such as craft of horn, leather, fur, bones from animals sick / dead because the disease anthrax.
- Community Health Center is required to report to the District Health Office / City if
meet the patient / suspect anthrax.

Abortion

Abortion

Definition of abortion
Interruption of the pregnancy before the fetus can survive outside the womb.
As restrictions are used less than 22 weeks gestation or fetal weight
less than 500 grams.

Cause
of abortion
Large part due to chromosomal abnormalities products of conception. Some
Other causes are trauma, content and tools for abnormalities that are not
known.

Clinical Overview
of abortion

- The symptoms of pregnancy (missed period, nausea / vomiting in the morning) that
accompanied by vaginal bleeding (spotting started to gather) and / or
lower abdominal pain, leading to a diagnosis of abortion.
- Abortion Imminens (Threat of Miscarriage)
Marked with a little vaginal bleeding, abdominal pain does not exist or
slightly. There are currently no opening of the cervix
- Insipiens abortion (miscarriage is in progress)
Vaginal bleeding a lot (to be lumpy), abdominal pain
great, there is the opening of the cervix. Sometimes it seems the network results
conception in the ostium of the cervix.
- Inkompletus Abortion (Incomplete Miscarriage)
Many vaginal bleeding, severe abdominal pain sedangsampai. History
out most of the conceptus tissue, cervical ostium can still open
or closing.
- Abortion Kompletus (incomplete miscarriage)
Vaginal bleeding begins to decline - stop, without abdominal pain, ostium
the cervix is ​​closed. Out the history of the conceptus tissue intact, entirely.
- Missed Abortion (Miscarriage is retained)
Abortion with retained products of conception for 2 weeks of intra uterine
or more. History of vaginal bleeding a little, without abdominal pain, ostium
cervix is ​​still closed. Enlargement of the uterus is not appropriate (smaller) than the age
gestation should be.

Diagnosis of abortion
- Late menstruation (amenorhea) less than 22 weeks.
- Vaginal bleeding, possibly accompanied by network products of conception.
- Pain in the upper region simpisis.
- The opening of the ostium of the cervix.

Management
of abortion
In the non-care centers:

•  Abortion Imminens
- Bed rest at least 2-3 hours (preferably hospitalization)
- Abstaining from sexual intercourse
- After 3 days bed rest, re-evaluation of diagnosis, when abortion was still
imminens bed rest on the move
- Gradual mobilization (sitting - standing - walking) began when believed
no vaginal bleeding 24 hours

•  Abortion next level
- If possible to do the stabilization of the general state of the liberation of the road
breath, providing oxygenation (O2 2-4 liters per minute), the installation of a liquid
intravenous crystalloid (lactated Ringer / Ringer Acetate / NaCl 0.9%) in accordance
resuscitation guidelines.
- The patient was referred after vital signs within normal limits to health center
Care or hospital

At the health center care
•  Abortion Imminens
- As in the non-care health center
•  Abortion Insipiens
- Prophylactic antibiotics: Ampicillin iv before curettage action.
- Need immediate expenditure of the POC and discharge cavity
uteri. Abortion can be performed with forceps, spoon curette, and suction curettage
- Uterotonic: Oxytocin 10 IU i.m

•  Abortion Inkompletus
Needs to be done emptying the uterus cavity. Can be done
with abortion forceps, spoon curette, and suction curettage
- Immediately tackle emergencies:
A. Oxygenation 2-4 liters / minute
2. Iv crystalloid fluids (0.9% NaCl, Ringer's lactate, Ringer
Acetate)
3. Transfusion when the hemoglobin is less than '
3d 8 g / dl
•  Abortion Kompletus
- Evaluation is there any abortion complications (anemia and infection)
- When encountered complications, treatment adjusted
- If no complications, no need for special management.
•  Missed Abortion
- Evaluation of routine hematology (hemoglobin, hematocrit, leukocytes, platelets)
and test of hemostasis (fibrinogen, bleeding time, clotting time).
- If there is hemostasis disorders and hipofibrinogenemia physiology, immediately refer
in a hospital that is able to transfuse platelets / Buffy-Coat and
other blood components.
- The conception needs to be evacuated from the uterine cavity. Implemented after the
certainly there is no interference hemostasis physiology.